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mpp4a MAGUK p55 scaffold protein 4a [ Danio rerio (zebrafish) ]

Gene ID: 100535324, updated on 9-Dec-2024

Summary

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Official Symbol
mpp4aprovided by ZNC
Official Full Name
MAGUK p55 scaffold protein 4aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070912-523
See related
Ensembl:ENSDARG00000058222 AllianceGenome:ZFIN:ZDB-GENE-070912-523
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-33m14.4
Summary
Predicted to be located in membrane. Predicted to be active in adherens junction and plasma membrane. Orthologous to human MPP4 (MAGUK p55 scaffold protein 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See mpp4a in Genome Data Viewer
Location:
chromosome: 9
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (13681965..13714118)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (13711059..13743185)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene transfer RNA glutamine (anticodon UUG) Neighboring gene alsin Rho guanine nucleotide exchange factor ALS2 a Neighboring gene transmembrane protein 237a Neighboring gene abl-interactor 2a Neighboring gene uncharacterized LOC137496457

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MAGUK p55 subfamily member 4
Names
membrane palmitoylated protein 4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
mpp4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    13681965..13714118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068223563.1 → XP_068079664.1  MAGUK p55 subfamily member 4 isoform X3

  2. XM_021478856.2 → XP_021334531.1  MAGUK p55 subfamily member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PSE8
    Conserved Domains (5) summary
    smart00569
    Location:24 → 76
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    smart00228
    Location:147 → 230
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam02828
    Location:84 → 133
    L27; L27 domain
    cl17036
    Location:241 → 300
    SH3; Src Homology 3 domain superfamily
    cl27059
    Location:418 → 609
    Guanylate_kin; Guanylate kinase

  3. XM_021478855.2 → XP_021334530.1  MAGUK p55 subfamily member 4 isoform X1

    UniProtKB/TrEMBL
    A0A286Y9N6, A0A8M3AVU8
    Related
    ENSDARP00000143320.1, ENSDART00000175639.2
    Conserved Domains (5) summary
    smart00569
    Location:24 → 76
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    smart00228
    Location:147 → 230
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam02828
    Location:84 → 133
    L27; L27 domain
    cl17036
    Location:241 → 300
    SH3; Src Homology 3 domain superfamily
    cl27059
    Location:419 → 610
    Guanylate_kin; Guanylate kinase

RNA

  1. XR_011016797.1 RNA Sequence

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394743.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    412498..444651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068218533.1 → XP_068074634.1  MAGUK p55 subfamily member 4 isoform X3

  2. XM_021472139.2 → XP_021327814.1  MAGUK p55 subfamily member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PSE8
    Conserved Domains (5) summary
    smart00569
    Location:24 → 76
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    smart00228
    Location:147 → 230
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam02828
    Location:84 → 133
    L27; L27 domain
    cl17036
    Location:241 → 300
    SH3; Src Homology 3 domain superfamily
    cl27059
    Location:418 → 609
    Guanylate_kin; Guanylate kinase

  3. XM_009304537.4 → XP_009302812.1  MAGUK p55 subfamily member 4 isoform X1

    UniProtKB/TrEMBL
    A0A286Y9N6, A0A8M3AVU8
    Conserved Domains (5) summary
    smart00569
    Location:24 → 76
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    smart00228
    Location:147 → 230
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam02828
    Location:84 → 133
    L27; L27 domain
    cl17036
    Location:241 → 300
    SH3; Src Homology 3 domain superfamily
    cl27059
    Location:419 → 610
    Guanylate_kin; Guanylate kinase

RNA

  1. XR_011009759.1 RNA Sequence

Nucleotide Protein
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