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MIR3913-2 microRNA 3913-2 [ Homo sapiens (human) ]

Gene ID: 100500868, updated on 17-Sep-2024

Summary

Official Symbol
MIR3913-2provided by HGNC
Official Full Name
microRNA 3913-2provided by HGNC
Primary source
HGNC:HGNC:38953
See related
Ensembl:ENSG00000283677 miRBase:MI0016418; AllianceGenome:HGNC:38953
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
mir-3913-2
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR3913-2 in Genome Data Viewer
Location:
12q15
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (69584723..69584822)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (69563639..69563738)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (69978503..69978602)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2373 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr12:69860555-69861168 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:69863839-69864340 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6651 Neighboring gene fibroblast growth factor receptor substrate 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6652 Neighboring gene small nucleolar RNA, H/ACA box 113 Neighboring gene MPRA-validated peak1784 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6653 Neighboring gene microRNA 3913-1 Neighboring gene chaperonin containing TCP1 subunit 2 Neighboring gene leucine rich repeat containing 10

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037476.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC018921
    Related
    ENST00000637916.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    69584723..69584822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    69563639..69563738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)