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Zfp687 zinc finger protein 687 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100363361, updated on 4-Jan-2025

Summary

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Official Symbol
Zfp687provided by RGD
Official Full Name
zinc finger protein 687provided by RGD
Primary source
RGD:2323182
See related
EnsemblRapid:ENSRNOG00000021026 AllianceGenome:RGD:2323182
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA binding activity. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Paget's disease of bone 6. Orthologous to human ZNF687 (zinc finger protein 687). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Adrenal (RPKM 31.1), Thymus (RPKM 27.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp687 in Genome Data Viewer
Location:
2q34
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (185261903..185270651, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (182572893..182581641, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (196172266..196180946, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene regulatory factor X5 Neighboring gene phosphatidylinositol 4-kinase beta Neighboring gene uncharacterized LOC102547008 Neighboring gene proteasome 26S subunit ubiquitin receptor, non-ATPase 4 Neighboring gene uncharacterized LOC134485649

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 687

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427731.1 → NP_001414660.1  zinc finger protein 687

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    D3ZT56
    Related
    ENSRNOP00000028553.4, ENSRNOT00000028553.9

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    185261903..185270651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006232935.4 → XP_006232997.1  zinc finger protein 687 isoform X1

    See identical proteins and their annotated locations for XP_006232997.1

    UniProtKB/TrEMBL
    D3ZT56
    Conserved Domains (3) summary
    sd00017
    Location:964 → 984
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:794 → 876
    zf-C2H2_8; C2H2-type zinc ribbon
    pfam16622
    Location:1129 → 1157
    zf-C2H2_11; zinc-finger C2H2-type

  2. XM_002729081.6 → XP_002729127.1  zinc finger protein 687 isoform X1

    See identical proteins and their annotated locations for XP_002729127.1

    UniProtKB/TrEMBL
    D3ZT56
    Conserved Domains (3) summary
    sd00017
    Location:964 → 984
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:794 → 876
    zf-C2H2_8; C2H2-type zinc ribbon
    pfam16622
    Location:1129 → 1157
    zf-C2H2_11; zinc-finger C2H2-type

  3. XM_006232934.4 → XP_006232996.1  zinc finger protein 687 isoform X1

    See identical proteins and their annotated locations for XP_006232996.1

    UniProtKB/TrEMBL
    D3ZT56
    Conserved Domains (3) summary
    sd00017
    Location:964 → 984
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:794 → 876
    zf-C2H2_8; C2H2-type zinc ribbon
    pfam16622
    Location:1129 → 1157
    zf-C2H2_11; zinc-finger C2H2-type
Nucleotide Protein Strain
Heading Accession and Version

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