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ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100345841, updated on 17-Dec-2024

Summary

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Gene symbol
ABCC1
Gene description
ATP binding cassette subfamily C member 1 (ABCC1 blood group)
See related
Ensembl:ENSOCUG00000017956
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
MRP1
Orthologs
human mouse all
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Genomic context

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See ABCC1 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 19 NC_091450.1 (19232235..19363045)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 6 NC_067379.1 (10819474..10951023, complement)

Chromosome 19 - NC_091450.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103348573 Neighboring gene centrosomal protein 20 Neighboring gene U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein pseudogene Neighboring gene ATP binding cassette subfamily C member 6 Neighboring gene BOS complex subunit NOMO1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multidrug resistance protein 1 (MRP1) in rabbit conjunctival epithelial cells: its effect on drug efflux and its regulation by adenoviral infection. Yang JJ, et al. Pharm Res, 2007 Aug. PMID 17404811
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MRP1 appears to be primarily localized in the basolateral membrane of conjunctival epithelial cells and functions in the efflux of certain organic anions and inflammatory factors
    Title: Multidrug resistance protein 1 (MRP1) in rabbit conjunctival epithelial cells: its effect on drug efflux and its regulation by adenoviral infection.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type xenobiotic transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutathione transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in xenobiotic transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
multidrug resistance-associated protein 1
Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ATP-binding cassette, sub-family C, member 1
multiple drug resistance protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091450.1 Reference mOryCun1.1

    Range
    19232235..19363045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051847486.2 → XP_051703446.2  multidrug resistance-associated protein 1

    UniProtKB/TrEMBL
    G1TVN1
Nucleotide Protein
Heading Accession and Version

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