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pitpnab phosphatidylinositol transfer protein, alpha b [ Danio rerio (zebrafish) ]

Gene ID: 100333060, updated on 9-Dec-2024

Summary

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Official Symbol
pitpnabprovided by ZNC
Official Full Name
phosphatidylinositol transfer protein, alpha bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-110408-51
See related
Ensembl:ENSDARG00000044091 AllianceGenome:ZFIN:ZDB-GENE-110408-51
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-213e17.2
Summary
Predicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to act upstream of or within phospholipid transport. Predicted to be active in cytoplasm. Orthologous to human PITPNA (phosphatidylinositol transfer protein alpha). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See pitpnab in Genome Data Viewer
Location:
chromosome: 10
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (24323753..24371339, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (24351698..24401949, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene glucan (1,4-alpha-), branching enzyme 1a Neighboring gene inositol polyphosphate-5-phosphatase Kb Neighboring gene solute carrier family 43 member 2b Neighboring gene hephaestin-like 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The central nervous system transcriptome of the weakly electric brown ghost knifefish (Apteronotus leptorhynchus): de novo assembly, annotation, and proteomics validation. Salisbury JP, et al. BMC Genomics, 2015 Mar 11. PMID 25879418, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylcholine binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylcholine transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phospholipid transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phospholipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
phosphatidylinositol transfer protein alpha isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    24323753..24371339 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479347.2 → XP_021335022.1  phosphatidylinositol transfer protein alpha isoform

    UniProtKB/TrEMBL
    A0A8M1RHH5, F8W544
    Related
    ENSDARP00000124103.1, ENSDART00000149362.3
    Conserved Domains (1) summary
    cd08888
    Location:2 → 257
    SRPBCC_PITPNA-B_like; Lipid-binding SRPBCC domain of mammalian PITPNA, -B, and related proteins (Class I PITPs)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394785.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    346133..381327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002663555.6 → XP_002663601.1  phosphatidylinositol transfer protein alpha isoform

    UniProtKB/TrEMBL
    A0A8M1RHH5, F8W544
    Conserved Domains (1) summary
    cd08888
    Location:2 → 257
    SRPBCC_PITPNA-B_like; Lipid-binding SRPBCC domain of mammalian PITPNA, -B, and related proteins (Class I PITPs)
Nucleotide Protein
Heading Accession and Version

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