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stk31 serine/threonine kinase 31 [ Danio rerio (zebrafish) ]

Gene ID: 100330765, updated on 9-Dec-2024

Summary

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Official Symbol
stk31provided by ZNC
Official Full Name
serine/threonine kinase 31provided by ZNC
Primary source
ZFIN:ZDB-GENE-140106-59
See related
AllianceGenome:ZFIN:ZDB-GENE-140106-59
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
TDRD8
Summary
Predicted to enable ATP binding activity and protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Orthologous to human STK31 (serine/threonine kinase 31). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See stk31 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (21492288..21539735, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (21701569..21733727, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene gasdermin Eb Neighboring gene protein associated with LIN7 2, MAGUK p55 family member a Neighboring gene discoidin domain receptor tyrosine kinase 1 Neighboring gene guanine nucleotide binding protein-like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Comparative studies on duplicated tdrd7 paralogs in teleosts: Molecular evolution caused neo-functionalization. Wang B, et al. Comp Biochem Physiol Part D Genomics Proteomics, 2019 Jun. PMID 31059868
  2. Tdrd12 Is Essential for Germ Cell Development and Maintenance in Zebrafish. Dai X, et al. Int J Mol Sci, 2017 Jun 7. PMID 28590408, Free PMC Article
  3. The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1β maturation and gasdermin E-mediated pyroptosis. Li JY, et al. J Biol Chem, 2020 Jan 24. PMID 31852739, Free PMC Article
  4. Expressed sequence tag analysis of expression profiles of zebrafish testis and ovary. Zeng S, et al. Gene, 2002 Jul 10. PMID 12234666
  5. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine/threonine-protein kinase 31
Names
zmp:0000001099
NP_001373360.1
XP_068069956.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386431.1 → NP_001373360.1  serine/threonine-protein kinase 31

    Status: VALIDATED

    Source sequence(s)
    LO018025
    Conserved Domains (3) summary
    COG1196
    Location:291 → 687
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl02573
    Location:41 → 111
    Tudor_SF; Tudor domain superfamily
    cl21453
    Location:802 → 922
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    21492288..21539735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213855.1 → XP_068069956.1  serine/threonine-protein kinase 31 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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