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rap1gap2b RAP1 GTPase activating protein 2b [ Danio rerio (zebrafish) ]

Gene ID: 100170821, updated on 9-Dec-2024

Summary

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Official Symbol
rap1gap2bprovided by ZNC
Official Full Name
RAP1 GTPase activating protein 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080722-11
See related
Ensembl:ENSDARG00000074222 AllianceGenome:ZFIN:ZDB-GENE-080722-11
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:175145
Summary
Predicted to enable GTPase activator activity. Predicted to act upstream of or within regulation of small GTPase mediated signal transduction. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human RAP1GAP2 (RAP1 GTPase activating protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See rap1gap2b in Genome Data Viewer
Location:
chromosome: 21
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (31015524..31144018, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (30983604..31107208, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene post-GPI attachment to proteins 2 Neighboring gene nuclear cap binding subunit 3 Neighboring gene transfer RNA serine (anticodon UGA) Neighboring gene transfer RNA alanine (anticodon CGC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
rap1 GTPase-activating protein 2b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130656.2 → NP_001124128.2  rap1 GTPase-activating protein 2b isoform 2

    Status: VALIDATED

    Source sequence(s)
    CR391971, CT574573
    UniProtKB/TrEMBL
    B3DLK3
    Related
    ENSDARP00000100814.1, ENSDART00000111571.2

  2. NM_001423699.1 → NP_001410628.1  rap1 GTPase-activating protein 2b isoform 1

    Status: VALIDATED

    Source sequence(s)
    CR391971, CT574573
    UniProtKB/TrEMBL
    B3DLK3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    31015524..31144018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068215763.1 → XP_068071864.1  rap1 GTPase-activating protein 2b isoform X3

    UniProtKB/TrEMBL
    B3DLK3

  2. XM_068215762.1 → XP_068071863.1  rap1 GTPase-activating protein 2b isoform X2

    UniProtKB/TrEMBL
    B3DLK3

  3. XM_068215761.1 → XP_068071862.1  rap1 GTPase-activating protein 2b isoform X1

    UniProtKB/TrEMBL
    B3DLK3
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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