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fdx1 ferredoxin 1 [ Danio rerio (zebrafish) ]

Gene ID: 100126232, updated on 4-Jan-2025

Summary

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Official Symbol
fdx1provided by ZNC
Official Full Name
ferredoxin 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-071015-2
See related
Ensembl:ENSDARG00000056410 AllianceGenome:ZFIN:ZDB-GENE-071015-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:6907289
Summary
Predicted to enable electron transfer activity. Acts upstream of or within negative regulation of epiboly involved in gastrulation with mouth forming second. Predicted to be active in mitochondrion. Is expressed in brain; digestive system; heart; and pleuroperitoneal region. Orthologous to human FDX1 (ferredoxin 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See fdx1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (29520786..29527021)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (29709955..29716275)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene si:dkey-46k9.4 Neighboring gene uncharacterized LOC137490359 Neighboring gene Rho GTPase activating protein 20 Neighboring gene ring finger protein 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Ferredoxin 1b (Fdx1b) Is the Essential Mitochondrial Redox Partner for Cortisol Biosynthesis in Zebrafish. Griffin A, et al. Endocrinology, 2016 Mar. PMID 26650568, Free PMC Article
  2. Expression and activity profiling of the steroidogenic enzymes of glucocorticoid biosynthesis and the fdx1 co-factors in zebrafish. Weger M, et al. J Neuroendocrinol, 2018 Apr. PMID 29486070
  3. The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafish. Auer RL, et al. Br J Haematol, 2007 Jun. PMID 17488487
  4. Analyses of mRNA structure dynamics identify embryonic gene regulatory programs. Beaudoin JD, et al. Nat Struct Mol Biol, 2018 Aug. PMID 30061596, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Larvae with genetic disruption of fdx1b were morphologically inconspicuous.
    Title: Ferredoxin 1b (Fdx1b) Is the Essential Mitochondrial Redox Partner for Cortisol Biosynthesis in Zebrafish.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables electron transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within P450-containing electron transport chain IEA
Inferred from Electronic Annotation
more info
  
involved_in electron transport chain IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within negative regulation of epiboly involved in gastrulation with mouth forming second IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
adrenodoxin, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    29520786..29527021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478966.2 → XP_021334641.1  adrenodoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8M1QKT2, E7F7J1
    Related
    ENSDARP00000113657.1, ENSDART00000144430.3
    Conserved Domains (1) summary
    PLN02593
    Location:53 → 155
    PLN02593; adrenodoxin-like ferredoxin protein

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394759.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    125901..132136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001922687.5 → XP_001922722.2  adrenodoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8M1QKT2, E7F7J1
    Conserved Domains (1) summary
    PLN02593
    Location:53 → 155
    PLN02593; adrenodoxin-like ferredoxin protein
Nucleotide Protein Strain
Heading Accession and Version

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