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Pnrc2 proline-rich nuclear receptor coactivator 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 100125373, updated on 27-Nov-2024

Summary

Symbol
Pnrc2provided by RGD
Full Name
proline-rich nuclear receptor coactivator 2provided by RGD
Primary source
RGD:1642418
See related
EnsemblRapid:ENSRNOG00000070268 AllianceGenome:RGD:1642418
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in P-body and nucleus. Orthologous to human PNRC2 (proline rich nuclear receptor coactivator 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 814.9), Spleen (RPKM 697.8) and 9 other tissues See more
Orthologs
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Genomic context

See Pnrc2 in Genome Data Viewer
Location:
5q36
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (153387522..153390506, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (148103966..148106950, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (154220552..154223536, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P2-like Neighboring gene serine and arginine rich splicing factor 10 Neighboring gene cannabinoid receptor 2 Neighboring gene alpha-L-fucosidase 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC93828

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in P-body ISO
Inferred from Sequence Orthology
more info
 
located_in P-body ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
proline-rich nuclear receptor coactivator 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103360.1NP_001096830.1  proline-rich nuclear receptor coactivator 2

    See identical proteins and their annotated locations for NP_001096830.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081903
    UniProtKB/Swiss-Prot
    Q66HE1
    UniProtKB/TrEMBL
    A6IT73
    Related
    ENSRNOP00000084836.1, ENSRNOT00000104557.2
    Conserved Domains (1) summary
    pfam15365
    Location:88106
    PNRC; Proline-rich nuclear receptor coactivator motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    153387522..153390506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)