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Cep85l centrosomal protein 85-like [ Mus musculus (house mouse) ]

Gene ID: 100038725, updated on 9-Dec-2024

Summary

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Official Symbol
Cep85lprovided by MGI
Official Full Name
centrosomal protein 85-likeprovided by MGI
Primary source
MGI:MGI:3642684
See related
Ensembl:ENSMUSG00000038594 AllianceGenome:MGI:3642684
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm9766; 1700003O08Rik
Summary
Predicted to be involved in neuron migration. Predicted to be located in pericentriolar material. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in lissencephaly 10. Orthologous to human CEP85L (centrosomal protein 85 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in testis adult (RPKM 10.2), lung adult (RPKM 1.5) and 18 other tissues See more
Orthologs
human all
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Genomic context

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See Cep85l in Genome Data Viewer
Location:
10 B3; 10
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (53149537..53256765, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (53273441..53379883, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40649 Neighboring gene STARR-seq mESC enhancer starr_26690 Neighboring gene predicted gene, 36173 Neighboring gene predicted gene, 19395 Neighboring gene transaldolase 1 pseudogene Neighboring gene phospholamban Neighboring gene STARR-seq mESC enhancer starr_26692 Neighboring gene predicted gene, 36229 Neighboring gene STARR-seq mESC enhancer starr_26693 Neighboring gene transmembrane protein 229B, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics. Voisinne G, et al. Nat Immunol, 2019 Nov. PMID 31591574, Free PMC Article
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Hein MY, et al. Cell, 2015 Oct 22. PMID 26496610
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in neuron migration IEA
Inferred from Electronic Annotation
more info
  
involved_in neuron migration ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in pericentriolar material IEA
Inferred from Electronic Annotation
more info
  
located_in pericentriolar material ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
centrosomal protein of 85 kDa-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204983.2 → NP_001191912.1  centrosomal protein of 85 kDa-like

    See identical proteins and their annotated locations for NP_001191912.1

    Status: VALIDATED

    Source sequence(s)
    AC105169, AC153524
    Consensus CDS
    CCDS56701.1
    UniProtKB/Swiss-Prot
    A0A1W2P884
    Related
    ENSMUSP00000151909.2, ENSMUST00000220443.2
    Conserved Domains (1) summary
    COG1196
    Location:442 → 742
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    53149537..53256765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512494.5 → XP_006512557.1  centrosomal protein of 85 kDa-like isoform X2

    UniProtKB/TrEMBL
    E9QA61
    Related
    ENSMUSP00000152032.2, ENSMUST00000220376.2
    Conserved Domains (1) summary
    COG1196
    Location:340 → 640
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_036155444.1 → XP_036011337.1  centrosomal protein of 85 kDa-like isoform X1

    Conserved Domains (1) summary
    COG1196
    Location:430 → 730
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_017313744.3 → XP_017169233.1  centrosomal protein of 85 kDa-like isoform X2

    UniProtKB/TrEMBL
    E9QA61
    Related
    ENSMUSP00000093356.7, ENSMUST00000095691.7
    Conserved Domains (1) summary
    COG1196
    Location:340 → 640
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  4. XM_017313743.3 → XP_017169232.1  centrosomal protein of 85 kDa-like isoform X2

    UniProtKB/TrEMBL
    E9QA61
    Conserved Domains (1) summary
    COG1196
    Location:340 → 640
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A1W2P884.1 GenPept UniProtKB/Swiss-Prot:A0A1W2P884

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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