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cckb cholecystokinin b [ Danio rerio (zebrafish) ]

Gene ID: 100000095, updated on 12-Jan-2025

Summary

Official Symbol
cckbprovided by ZNC
Official Full Name
cholecystokinin bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060720-30
See related
Ensembl:ENSDARG00000100052 AllianceGenome:ZFIN:ZDB-GENE-060720-30
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fq26c12
Summary
Predicted to enable neuropeptide hormone activity. Predicted to be involved in digestion. Predicted to be located in extracellular region. Predicted to be active in axon and extracellular space. Is expressed in Rohon-Beard neurons; brain; habenula; and trigeminal ganglion. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human CCK (cholecystokinin). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See cckb in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_003335800.1 (1688..8430)
105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003335800.1 (1653..8430)

NW_003335800.1Genomic Context describing neighboring genes Neighboring gene trafficking kinesin-binding protein 1-like Neighboring gene trafficking protein, kinesin binding 1b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
 
enables neuropeptide hormone activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neuropeptide hormone activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in digestion IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within digestion IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NW_003335800.1 Reference GRCz11 Primary Assembly

    Range
    1688..8430
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002665615.7XP_002665661.2  cholecystokinin

    UniProtKB/TrEMBL
    A0A0R4IHW0, A0A8M1RE78
    Related
    ENSDARP00000132941.1, ENSDART00000163899.2
    Conserved Domains (1) summary
    pfam00918
    Location:4117
    Gastrin; Gastrin/cholecystokinin family