GEO DataSets

(Submitter supplied) As part of the EcoToxChip project, 49 distinct exposure studies were conducted on three lab model species (Japanese quail, fathead minnow, African clawed frog) and three ecologically relevant species (double crested cormorant, rainbow trout, northern leopard frog), at multiple life stages (embryo, adult), exposed to eight chemicals of environmental concern (ethinyl estradiol-EE2, hexabromocyclododecane-HBCD, lead-Pb, selenomethionine-SeMe, 17β trenbolone-TB, chlorpyrifos-CPF, fluoxetine-FLX, and benzo [a] pyrene-BaP. more...

Organism:

Phalacrocorax auritus; Pimephales promelas; Lithobates pipiens; Oncorhynchus mykiss; Xenopus laevis; Coturnix japonica

Type:

Expression profiling by high throughput sequencing

9 related Platforms

724 Samples

Download data: TXT

(Submitter supplied) Abstract: Natural communities of microbes inhabiting amphibian skin, the skin microbiome, are critical to supporting amphibian health and disease resistance. To enable the pro-active health assessment and management of amphibians on Army installations and beyond, we investigated the effects of acute (96h) munitions exposures to Rana pipiens (leopard frog) tadpoles and the associated skin microbiome, integrated with RNAseq-based transcriptomic responses in the tadpole host. more...

Organism:

Lithobates pipiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28905

72 Samples

Download data: FASTA, TXT

(Submitter supplied) Nanoparticles (<100 nm) are engineered to have unique physico-chemical properties compared to their larger counterparts. Nanosilver (nAg) is the most prevalent nanoparticle in consumer products due to its strong antimicrobial action. While nAg toxicity at high concentrations has been well described, the potential for sublethal effects at or below regulatory guidelines is relatively unknown. Amphibian metamorphosis is mediated by thyroid hormone (TH) and can be precociously induced by the addition of exogenous hormone. more...

Organism:

Xenopus laevis; Aquarana catesbeiana; Lithobates pipiens

Type:

Expression profiling by array

Platform:

GPL16276

72 Samples

Download data: TXT

(Submitter supplied) Nanoparticles (NPs) are engineered in the nanoscale (<100nm) to have unique physico-chemical properties from their bulk counterparts. Nanosilver (nAg) is the most prevalent nanoparticle in consumer products due to its strong antimicrobial action. While nAg toxicity at high concentrations has been well described, the sublethal effects at or below regulatory guidelines are relatively unknown. Amphibian metamorphosis is mediated by thyroid hormone (TH), and initial studies indicate that low concentrations of nAg disrupt TH-dependent responses in precociously induced premetamorphic bullfrog (Rana catesbeiana) tadpoles. more...

Organism:

Xenopus laevis; Aquarana catesbeiana; Lithobates pipiens

Type:

Expression profiling by array

Platform:

GPL16276

60 Samples

Download data: TXT

(Submitter supplied) An anthropogenic chemical contaminant commonly identified in aquatic receiving environments is the non-steroidal anti-inflammatory drug (NSAID), ibuprofen(IBF). While the role of ibuprofen in target organisms is known, there exists a paucity of data on the impact of exposure to non-target wildlife species. In the case of frog species, normal development and environmental fitness involves the actions of the thyroid hormones (THs), particularly at key points in the life cycle. more...

Organism:

Xenopus laevis; Aquarana catesbeiana; Lithobates pipiens

Type:

Expression profiling by array

Platform:

GPL16276

24 Samples

Download data: TXT

(Submitter supplied) Traditionally, the study of evolution has focused on heritable variation, because selection on non-heritable phenotypic variation was deemed non-important for its inability to cause evolutionary responses such as diversification of lineages. Recently however, it has been suggested that also environmentally induced phenotypic variation such as phenotypic plasticity can play an important role in adaptive responses resulting in diversification. more...

Organism:

Xenopus laevis; Aquarana catesbeiana; Rana temporaria; Lithobates pipiens

Type:

Expression profiling by array

Platform:

GPL16276

48 Samples

Download data: TXT

(Submitter supplied) The impact of pesticides on amphibian metamorphosis may vary depending on developmental stage of individuals during the exposure period. Some anurans experience increased rates of development when exposure to the insecticide carbaryl occurs later in larval development. We exposed developing northern green frog tadpoles (Lithobates clamitans) to a 3 day pulsatile exposure of 1 mg/L carbaryl at 16 weeks relative to the starting free-swimming Gosner stage 25 (Gosner, 1960) and examined treatment effects on brain mRNA abundance profiles of Gosner stage 46 metamorphs using an amphibian cDNA microarray.

Organism:

Aquarana catesbeiana; Lithobates clamitans; Xenopus laevis; Lithobates pipiens

Type:

Expression profiling by array

Platform:

GPL16276

11 Samples

Download data: TXT

(Submitter supplied) MAGEX 2008 cDNA microarrays were printed on Erie C28 aminosilane (ThermoFisher Scientific) coated slides with a QArraymax microarray printer equipped with ArrayIt Stealth Technology SMP2 quill pins (TeleChem International Inc.) in a 48-pin tool that deposited ~ 0.1ng cDNA pieces per spot.  The cDNA fragments were spotted in 16 subgrids, each subgrid is 11x11 containing 119 spots (plus 2 blanks) with a spot pitch of 220 microns. more...

Organism:

Xenopus laevis; Aquarana catesbeiana; Lithobates pipiens

5 Series

215 Samples

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