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Items: 1 to 20 of 163

1.

Evolutionary changes in cis regulation are associated with altered chromatin activity and gene expression levels in the Drosophila eye development (RNA-Seq)

(Submitter supplied) Expression profiling by high-throughput sequencing (RNA-seq) across eight WT Drosophila species - D. melanogaster, D. simulans, D. yakuba, D. ananassae, D. pseudoobscura, D. willistoni, D. mojavensis and D. virilis - and three tissues, namely, brain, eye-antennal and imaginal discs, at the stage of third instar larvae.
Organism:
Drosophila simulans; Drosophila yakuba; Drosophila ananassae; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila melanogaster; Drosophila pseudoobscura
Type:
Expression profiling by high throughput sequencing
8 related Platforms
27 Samples
Download data: TXT
Series
Accession:
GSE59707
ID:
200059707
2.

Evolution of maternal and zygotic mRNA complements in the early Drosophila embryo

(Submitter supplied) The earliest stage of animal development is controlled by maternally deposited mRNA transcripts and proteins. Once the zygote is able to transcribe its own genome, maternal transcripts are degraded, in a tightly regulated process known as the maternal to zygotic transition (MZT). While this process has been well-studied within model species, we have little knowledge of how the pools of maternal and zygotic transcripts evolve. more...
Organism:
Drosophila persimilis; Drosophila santomea; Drosophila ananassae; Drosophila erecta; Drosophila miranda; Drosophila sechellia; Drosophila simulans; Drosophila virilis; Drosophila mauritiana; Drosophila mojavensis; Drosophila pseudoobscura; Drosophila willistoni; Drosophila melanogaster; Drosophila yakuba
Type:
Expression profiling by high throughput sequencing; Third-party reanalysis
14 related Platforms
119 Samples
Download data: TXT
Series
Accession:
GSE112858
ID:
200112858
3.

The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila sechellia; Drosophila simulans; Drosophila yakuba; Drosophila ananassae; Drosophila erecta; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila melanogaster; Drosophila pseudoobscura; Drosophila persimilis; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
15 related Platforms
175 Samples
Download data: BW
Series
Accession:
GSE102441
ID:
200102441
4.

The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes [evolutionary study]

(Submitter supplied) Transcriptional enhancers function as docking platforms for combinations of transcription factors to control gene expression. How enhancer sequences determine nucleosome occupancy, transcription factor recruitment, and transcriptional activation in vivo remains unclear. Using ATAC-seq across a panel of Drosophila inbred strains we found that SNPs affecting Grainyhead binding sites causally determine the accessibility of epithelial enhancers. more...
Organism:
Drosophila persimilis; Drosophila erecta; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila melanogaster; Drosophila pseudoobscura; Drosophila yakuba; Drosophila ananassae; Drosophila sechellia; Drosophila simulans
Type:
Genome binding/occupancy profiling by high throughput sequencing
12 related Platforms
24 Samples
Download data: BW
Series
Accession:
GSE102439
ID:
200102439
5.

Small RNAs from 11 Drosophila species

(Submitter supplied) Annotation of small RNAs from 11 Drosophila species for the purpose of non-coding RNA annotation and comparative genomics assessment.
Organism:
Drosophila grimshawi; Drosophila sechellia; Drosophila simulans; Drosophila yakuba; Drosophila ananassae; Drosophila erecta; Drosophila virilis; Drosophila pseudoobscura; Drosophila mojavensis; Drosophila persimilis; Drosophila willistoni
Type:
Non-coding RNA profiling by high throughput sequencing
22 related Platforms
56 Samples
Download data: TXT
Series
Accession:
GSE98013
ID:
200098013
6.

RNA-seq of sexed adult tissues/body parts from eight Drosophila species

(Submitter supplied) This data set contains polyA+ transcriptional profiling of sexed adult tissues/body parts and whole adults of eight Drosophila species: Drosophila melanogaster (FBsp00000001) from two strains [w1118 (FBst0005905) and Oregon-R (FBst0025211)], Drosophila yakuba (FBsp00000254), Drosophila ananassae (FBsp00000052), Drosophila pseudoobscura (FBsp00000201), Drosophila persimilis (FBsp00000188), Drosophila willistoni (FBsp00000253), Drosophila mojavensis (FBsp00000160), and Drosophila virilis (FBsp00000251). more...
Organism:
Drosophila yakuba; synthetic construct; Drosophila mojavensis; Drosophila virilis; Drosophila willistoni; Drosophila ananassae; Drosophila persimilis; Drosophila melanogaster; Drosophila pseudoobscura
Type:
Expression profiling by high throughput sequencing
12 related Platforms
856 Samples
Download data: PDF, TXT
Series
Accession:
GSE99574
ID:
200099574
7.

roX ChIRP-seq in four Drosophila species

(Submitter supplied) We identified orthologs of the roX lncRNAs across diverse Drosophilid species, and then mapped the genomic binding sites of roX1 and roX2 in four Drosophila species (D. melanogaster, D. willistoni, D. virilis, and D. busckii) using ChIRP-seq (chromatin isolation by RNA Purification and sequencing), thus revealing the interplay of the evolution of roX1 and roX2 and their genomic binding sites.
Organism:
Drosophila virilis; Drosophila willistoni; Drosophila melanogaster; Drosophila busckii
Type:
Genome binding/occupancy profiling by high throughput sequencing
5 related Platforms
35 Samples
Download data: BED, BEDGRAPH, BW, FA, RTF, XLSX
Series
Accession:
GSE69208
ID:
200069208
8.

Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution

(Submitter supplied) Phenotypic differences between closely related species are thought to arise primarily from changes in gene expression due to mutations in cis-regulatory sequences (enhancers). However, it has remained unclear how frequently mutations alter enhancer activity or create functional enhancers de novo. Here we use STARR-seq, a recently developed quantitative enhancer assay, to determine genome-wide enhancer activity profiles for five Drosophila species in the constant trans-regulatory environment of Drosophila melanogaster S2 cells. more...
Organism:
Drosophila ananassae; Drosophila willistoni; Drosophila yakuba; Drosophila melanogaster; Drosophila pseudoobscura
Type:
Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing
5 related Platforms
18 Samples
Download data: TXT
Series
Accession:
GSE48251
ID:
200048251
9.

Sex-biased expression in Drosophila willistoni

(Submitter supplied) We performed mRNA sequencing of samples isolated from the heads, thoraxes, and abdomens of males and females of Drosophila willistoni to identify genes that are differentially expressed between the sexes.
Organism:
Drosophila willistoni
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL14358 GPL14359
8 Samples
Download data
Series
Accession:
GSE31723
ID:
200031723
10.

Illumina HiSeq 2000 (Drosophila ananassae; Drosophila willistoni; Drosophila yakuba)

Organism:
Drosophila ananassae; Drosophila yakuba; Drosophila willistoni
1 Series
56 Samples
Download data
Platform
Accession:
GPL23536
ID:
100023536
11.

Illumina NextSeq 500 (Drosophila willistoni)

Organism:
Drosophila willistoni
1 Series
5 Samples
Download data
Platform
Accession:
GPL20239
ID:
100020239
12.

Illumina HiSeq 2000 (Drosophila willistoni)

Organism:
Drosophila willistoni
8 Series
82 Samples
Download data
Platform
Accession:
GPL14359
ID:
100014359
13.

Illumina Genome Analyzer II (Drosophila willistoni)

Organism:
Drosophila willistoni
2 Series
7 Samples
Download data
Platform
Accession:
GPL14358
ID:
100014358
14.

RNA_Dwil_brain

Organism:
Drosophila willistoni
Source name:
brain
Platform:
GPL14359
Series:
GSE59707
Download data: TXT
Sample
Accession:
GSM1444033
ID:
301444033
15.

RNA_Dwil_wing

Organism:
Drosophila willistoni
Source name:
wing imaginal disc
Platform:
GPL14359
Series:
GSE59707
Download data: TXT
Sample
Accession:
GSM1444024
ID:
301444024
16.

RNA_Dwil_EA

Organism:
Drosophila willistoni
Source name:
eye-antennal imaginal disc
Platform:
GPL14359
Series:
GSE59707
Download data: TXT
Sample
Accession:
GSM1444015
ID:
301444015
17.

D. willistoni_stage5_replicate6

Organism:
Drosophila willistoni
Source name:
single embryo
Platform:
GPL14359
Series:
GSE112858
Download data
Sample
Accession:
GSM3090060
ID:
303090060
18.

D. willistoni_stage5_replicate5

Organism:
Drosophila willistoni
Source name:
single embryo
Platform:
GPL14359
Series:
GSE112858
Download data
Sample
Accession:
GSM3090059
ID:
303090059
19.

D. willistoni_stage5_replicate4

Organism:
Drosophila willistoni
Source name:
single embryo
Platform:
GPL14359
Series:
GSE112858
Download data
Sample
Accession:
GSM3090058
ID:
303090058
20.

D. willistoni_stage5_replicate3

Organism:
Drosophila willistoni
Source name:
single embryo
Platform:
GPL14359
Series:
GSE112858
Download data
Sample
Accession:
GSM3090057
ID:
303090057
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