GEO DataSets

(Submitter supplied) Our group recently transcriptomically characterized coculture growth between Streptococcus mutans and several species of commensal streptococci (Rose et al, 2023). However, these experiments were carried out in our lab-based experimental medium, tryptone and yeast extract (TY-). To understand whether culturing these species within a medium that more closely mimics their natural environment alters the interaction, we evaluated both monoculture and coculture growth between the dental caries pathogen Streptococcus mutans and oral commensal species Streptococcus oralis in a half TY- / half human saliva mix that was optimally chosen based on our initial characterization of oral streptococci behaviors in medium mixes containing saliva. more...

Organism:

Streptococcus oralis; Streptococcus mutans

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL33629 GPL33630 GPL24591

18 Samples

Download data: CSV

(Submitter supplied) RNA-Seq was used to compare the transcriptome of Streptococcus mutans UA159 during growth alone in monoculture, in coculture with Streptococcus gordonii DL1, Streptococcus sanguinis SK36 or Streptococcus oralis 34, and in a quadculture containing all four species. Individual cultures of commensal species Streptococcus gordonii DL1, Streptococcus sanguinis SK36 and Streptococcus oralis 34 were sequenced as well. more...

Organism:

Streptococcus sanguinis; Streptococcus mutans; Streptococcus oralis; Corynebacterium matruchotii; Streptococcus gordonii; Streptococcus sobrinus; Lacticaseibacillus casei; Streptococcus mutans UA159

Type:

Expression profiling by high throughput sequencing

11 related Platforms

33 Samples

Download data: CSV, XLSX

(Submitter supplied) To combat dental implant-associated infections, there is a need for novel materials which effectively inhibit bacterial biofilm formation. In the present study, a titanium surface functionalization based on the “slippery liquid-infused porous surfaces” (SLIPS) principle was analyzed in an oral flow chamber system. The immobilized liquid layer was stable over 13 days of continuous flow. With increasing flow rates, the surface exhibited a significant reduction in attached biofilm of both the oral initial colonizer Streptococcus oralis and an oral multi-species biofilm composed of S. more...

Organism:

Streptococcus oralis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26513

11 Samples

Download data: TXT

(Submitter supplied) Investigation of whole genome gene expression level changes in S. pneumoniae KCTC 5080T, S. mitis KCTC 3556T, S. oralis KCTC 13048T, and S. pseudopneumoniae CCUG 49455T. This proves that transcriptional profiling can facilitate in elucidating the genetic distance between closely related strains.

Organism:

Streptococcus pneumoniae R6; Streptococcus pseudopneumoniae ATCC BAA-960 = CCUG 49455; Streptococcus oralis; Streptococcus pneumoniae; Streptococcus mitis

Type:

Expression profiling by array

Platform:

GPL15485

4 Samples

Download data: CALLS, PAIR

(Submitter supplied) PFGRC has developed a cost effective alternative to complete genome sequencing in order to study the genetic differences between closely related species and/or strains. The comparative genomics approach combines Gene Discovery (GD) and Comparative Genomic Hybridization (CGH) techniques, resulting in the design and production of species microarrays that represent the diversity of a species beyond just the sequenced reference strain(s) used in the initial microarray design. more...

Organism:

Streptococcus pseudopneumoniae; Streptococcus pneumoniae; Streptococcus infantis; Streptococcus pneumoniae TIGR4; Streptococcus oralis SK255; Streptococcus oralis; Streptococcus mitis

Type:

Non-coding RNA profiling by array

Platform:

GPL13281

255 Samples

Download data: TXT