GEO DataSet Links for SRA (Select 18874139) - GEO DataSets

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Items: 2

Select item 3057694911.

NCCIT_SVA_minusDoxy_Rep1

Organism:: Homo sapiens

Source name:: SCi-NCCIT (- doxy)

Platform:: GPL24676
Series:: GSE192951

Download data: TSV

Sample

Accession:: GSM5769491

ID:: 305769491

SRA Run Selector

Select item 2001929512.

Specific genomic features underlie the co-option of SVA transposons as cis-regulatory elements in the human genome

(Submitter supplied) Domestication of transposable elements (TEs) into functional cis-regulatory elements is a widespread phenomenon. However, why some TEs are co-opted as functional enhancers while others are not is underappreciated. SINE-Vntr-Alus (SVAs) are the youngest group of transposons in the human genome, where ~3,700 copies are annotated, nearly half of which are human-exclusive. Many studies indicated that the SVAs are among the most frequently co-opted TEs in human gene regulation, but the mechanisms underlying such process have not yet been thoroughly investigated. more...