GEO DataSets

(Submitter supplied) Gene expression profiling of in vitro differentiated murine Th cell subsets. Flow cytometrically sorted naive Th cells (CD4+ CD44- Foxp3-) were polyclonally stimulated in vitro for 3 days using 4 µg/ml plate-bound antibody to CD3 (145-2C11) and 2 µg/ml soluble antibody to CD28 (PV-1). Th0 cells were cultured in the absence of exogenous cytokines. Th17 cells were differentiated with 50 ng/ml IL-6 plus 0.5 ng/ml TGF-β. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5166

Platform:

GPL6246

15 Samples

Download data: CEL, CHP

Analysis of naive CD4+ T cells stimulated with anti-CD3 and anti-CD28 antibodies in the absence of exogenous cytokines (Th0 cells), or differentiated with IL-27 plus TGF-β (Tr-1 cells) or with IL-6 plus TGF-β (Th17 cells). Results provide insight into the molecular bases of the T cell subsets.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 3 cell type sets

Platform:

GPL6246

Series:

GSE56021

15 Samples

Download data: CEL, CHP