GEO DataSet Links for PMC (Select 6075149) - GEO DataSets

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Items: 3

Select item 2001069251.

Epigenome editing of microsatellite repeat enhancers reveals specific regulatory functions and tumor dependencies

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL24268 GPL18573
41 Samples

Download data: BW

Series

Accession:: GSE106925

ID:: 200106925

PubMed Full text in PMC Similar studies

Select item 2001069152.

Epigenome editing of microsatellite repeat enhancers reveals specific regulatory functions and tumor dependencies [NRO-Seq]

(Submitter supplied) Various types of repetitive sequences are dysregulated in cancer but their contributions to oncogenesis are yet to be determined. Here we combine nascent transcription profiling with epigenome editing to test the function of GGAA microsatellites in Ewing sarcoma, a pediatric bone cancer where the oncogenic fusion protein EWS-FLI1 induces chromatin features of active enhancers at this class of repeats. more...