The evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation - - GEO DataSets

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The evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation

(Submitter supplied) Developmental programs often rely on parallel morphogenetic mechanisms that guarantee precise tissue architecture. While redundancy constitutes an obvious selective advantage, little is known on how novel morphogenetic mechanisms emerge during evolution. In zebrafish, rhombomeric boundaries behave as an elastic barrier, preventing cell intermingling between adjacent compartments. Here, we identify the fundamental role of the small-GTPase Rac3b in actomyosin cables assembly at hindbrain boundaries. more...

Organism:: Danio rerio

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other

Platform:: GPL18413
4 Samples

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Accession:: GSE109219

ID:: 200109219

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