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Regulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegans

(Submitter supplied) BACKGROUND: When resources are scant, C. elegans larvae arrest as long-lived dauers under the control of insulin/IGF- and TGFbeta-related signaling pathways. : We have identified genes that show different levels of expression in a comparison of wild-type L2 or L3 larvae (non-dauer) to TGFbeta mutants at similar developmental stages undergoing dauer formation. Many insulin/IGF pathway and other known dauer regulatory genes have changes in expression that suggest strong positive feedback by the TGFbeta pathway. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by array
4 related Platforms
10 Samples
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Series
Accession:
GSE4164
ID:
200004164

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