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Mature IgM+ plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge

(Submitter supplied) Dogma holds that plasma cells (PC), as opposed to B cells, cannot bind antigen (Ag) because they have switched from expression of membrane-bound immunoglobulins that constitute the B cell Ag receptor (BCR) to production of the secreted form of immunoglobulins. We have compared the phenotypical and functional attributes of PC generated by the T-cell-dependent and T-cell-independent forms of the hapten NP. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL21720
10 Samples
Download data: CEL
Series
Accession:
GSE80216
ID:
200080216

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