GEO DataSet Links for PMC (Select 4465988) - GEO DataSets

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Items: 3

Select item 2000629501.

DNA Methylation and RNA Expression Profiles in Lung Adenocarcinomas

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by array

Platforms:: GPL8432 GPL8490
112 Samples

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Accession:: GSE62950

ID:: 200062950

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000629492.

DNA Methylation and RNA Expression Profiles in Lung Adenocarcinomas [RNA Expression]

(Submitter supplied) Lung cancer occurs in never-smokers. Epigenetic changes in lung cancer potentially represent important diagnostic, prognostic, and therapeutic targets. We compared DNA methylation profiles of 28 adenocarcinomas of the lungs of never-smokers with paired adjacent nonmalignant lung tissue. We correlated differential methylation changes with gene expression changes from the same 28 samples. We observed a distinct separation in methylation profiles between tumor and adjacent nonmalignant lung tissue using principal component analysis. more...