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Global transcriptome analysis on Ankrd2 deficient or overexpressing differentiating primary myoblasts

(Submitter supplied) To provide insights into the role of Ankrd2 in the pathways controlling myogenic differentiation, the gene networks that are disturbed in Ankrd2 knockout or overexpressing primary cells were explored during differentiation. Ankrd2 plays an important role in myogenic differentiation by modulating the activity of its interacting partners (i.e p53). Since Ankrd2 binds to numerous transcription factors many signaling pathways remained to be explored to determine the functional significance of crosstalk between Ankrd2 and the activation of transcriptional programmes that regulate muscle remodeling. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10787
36 Samples
Download data: TXT
Series
Accession:
GSE43500
ID:
200043500

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