Reversible mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts - - GEO DataSets

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Reversible mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts

(Submitter supplied) Analysis of the transcriptional profiles of mRNA and microRNA in Rasless fibroblasts. 4-Hydroxy-tamoxifen (4-OHT) treatment triggers removal of K-Ras expression in [H-Ras-/-;N-Ras-/-;K-Raslox/lox;RERTert/ert ] mouse fibroblasts (named K-Raslox) generating “Rasless” MEFs which are unable to proliferate, but recover proliferative ability after ectopic expression of constitutively active downstream kinases such as BRAF and MEK1. more...

Organism:: Mus musculus; synthetic construct

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL8786 GPL1261
51 Samples

Download data: CEL

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Accession:: GSE45222

ID:: 200045222

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