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Simultaneous transcriptional profiling of bacteria and their host cells by heterogeneous RNA-Seq (hRNA-Seq)

(Submitter supplied) We developed heterogeneous RNA-Seq (hRNA-Seq) to simultaneously capture prokaryotic and eukaryotic expression profiles of bacteria-infected cells. As proof of principle, hRNA-Seq was applied to Chlamydia-infected cells, successfully obtaining the transcriptomes of both Chlamydia and their host cells at 1 and 24 hours post-infection. Substantial transcription was found in the immediate-early period of infection for both Chlamydia and the host cell. more...
Organism:
Homo sapiens; Chlamydia trachomatis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18031
4 Samples
Download data: TXT
Series
Accession:
GSE44253
ID:
200044253

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