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Mechanical loading and gene expression - Microarray study

(Submitter supplied) Skeletal integrity in humans and animals is maintained by daily mechanical loading. It has been widely accepted that osteocytes function as mechanosensors. Many biochemical signaling molecules are involved in the response of osteocytes to mechanical stimulation. The aim of this study was to identify genes involved in the translation of mechanical stimuli into bone formation. The four-point bending model was used to induce a single period of mechanical loading (comprising 300 cycles (2 Hz) using a peak magnitude of 60 N) on the right tibia, while the contra lateral left tibia served as control. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL1397
10 Samples
Download data: TXT
Series
Accession:
GSE50707
ID:
200050707

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