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Items: 2

1.

The effect of trichloroethylene on gene expression in mouse liver

(Submitter supplied) Trichloroethylene (TCE) is a widely used industrial chemical, and a common environmental contaminant. It is a well-known carcinogen in rodents and a probable carcinogen in humans. Studies utilizing panels of mouse inbred strains afford a unique opportunity to understand both metabolic and genetic basis for differences in responses to TCE. We tested the hypothesis that individual and liver-specific toxic effects of TCE are genetically controlled and that the mechanisms of toxicity and susceptibility can be uncovered by exploring responses to TCE using a diverse panel of inbred mouse strains. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3890
Platform:
GPL7202
94 Samples
Download data: TXT
Series
Accession:
GSE24278
ID:
200024278
2.
Full record GDS3890

Interstrain differences in the liver effects of trichloroethylene

Analysis of liver from multiple inbred strains 24hr after trichloroethylene (TCE) treatment. TCE is a widely used industrial chemical and a ubiquitous environmental contaminant. Results provide insight into the molecular mechanisms underlying interstrain differences in liver effects of TCE.
Organism:
Mus musculus
Type:
Expression profiling by array, log2 ratio, 2 agent, 16 strain sets
Platform:
GPL7202
Series:
GSE24278
94 Samples
Download data: TXT

Supplemental Content

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