GEO DataSet Links for PMC (Select 2225987) - GEO DataSets

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Items: 2

Select item 2000115241.

The platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease

(Submitter supplied) In sickle cell disease, ischemia-reperfusion injury and intravascular hemolysis produce endothelial dysfunction and vasculopathy characterized by reduced nitric oxide (NO) and arginine bioavailability. Recent functional studies of platelets in patients with sickle cell disease reveal a basally activated state, suggesting that pathological platelet activation may contribute to sickle cell disease vasculopathy. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3318
Platform:: GPL570
30 Samples

Download data: CEL

Series

Accession:: GSE11524

ID:: 200011524

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 33182.

Sickle cell disease: platelets

Analysis of platelets from patients with sickle cell disease. Sickle cell disease patients exhibit increased activation of platelets. Results provide insight into the molecular basis of platelet dysfunction in sickle cell disease.