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Items: 2

1.

Effect of BMP-2 on Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic Pulmonary Arterial Hypertension

(Submitter supplied) Bone morphogenetic proteins (BMP) inhibit proliferation and induce apoptosis in pulmonary artery smooth muscle cells (PASMC) from normal subjects. Dysfunction of BMP signaling due to mutations in and/or downregulation of BMP receptors has been implicated in idiopathic pulmonary arterial hypertension (IPAH). We examined whether BMP differentially regulates gene expression in PASMC from normal subjects and IPAH patients using the Affymetrix microarray analysis. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1372
Platform:
GPL8300
7 Samples
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Series
Accession:
GSE2559
ID:
200002559
2.
Full record GDS1372

Bone morphogenic protein 2 effect on idiopathic pulmonary arterial hypertension

Analysis of pulmonary artery smooth muscle cells (PASMC) from patients with idiopathic pulmonary arterial hypertension (IPAH). PASMC treated with 200 nM bone morphogenic protein 2 (BMP-2) for 24 hours. BMP signaling dysfunction has been implicated in IPAH.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 disease state sets
Platform:
GPL8300
Series:
GSE2559
7 Samples
Download data

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