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Items: 2

1.

Neuronal MML-1/MXL-2 regulates autophagic and peroxidase activity via glutamate transporter to prolong lifespan

(Submitter supplied) Accumulating evidence has demonstrated the presence of inter-tissue communication regulating systemic aging, but the underlying molecular network has not been fully explored. We and others previously showed that two basic helix-loop-helix transcription factors, MML-1 and HLH-30, are required for lifespan extension in several longevity paradigms, including germline-less Caenorhabditis elegans. However, it is unknown what tissues these factors target to promote longevity. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26672
16 Samples
Download data: XLSX
Series
Accession:
GSE234430
ID:
200234430

PubMed Full text in PMC Similar studies

2.

Neuronal HLH-30 regulates glp-1 longevity independent of neuronal MML-1/MXL-2

(Submitter supplied) Accumulating evidence has demonstrated the presence of inter-tissue communication regulating systemic aging, but the underlying molecular network has not been fully explored. We and others previously showed that two basic helix-loop-helix transcription factors, MML-1 and HLH-30, are required for lifespan extension in several longevity paradigms, including germline-less Caenorhabditis elegans. However, it is unknown what tissues these factors target to promote longevity. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26672
15 Samples
Download data: XLSX
Series
Accession:
GSE234429
ID:
200234429

PubMed Full text in PMC Similar studies

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