Gamma secretase inhibitor MRK-003 effect on pancreatic ductal adenocarcinoma tumor xenografts - - GEO DataSets

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Gamma secretase inhibitor MRK-003 effect on pancreatic ductal adenocarcinoma tumor xenografts

Analysis of 9 individual patient-derived, pancreatic ductal adenocarcinoma (PDAC) xenografts treated with GSI MRK-003. MRK-003 monotherapy significantly reduced tumor volume in 5 of 9 xenografts. Results provide insight into the molecular basis of MRK-003-mediated attenuation of PDAC.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 9 cell line, 2 other sets

Platform:: GPL570
Series:: GSE37645
18 Samples

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Accession:: GDS4342

ID:: 4342

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