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Full record GDS4342

Gamma secretase inhibitor MRK-003 effect on pancreatic ductal adenocarcinoma tumor xenografts

Analysis of 9 individual patient-derived, pancreatic ductal adenocarcinoma (PDAC) xenografts treated with GSI MRK-003. MRK-003 monotherapy significantly reduced tumor volume in 5 of 9 xenografts. Results provide insight into the molecular basis of MRK-003-mediated attenuation of PDAC.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 9 cell line, 2 other sets
Platform:
GPL570
Series:
GSE37645
18 Samples
Download data: CEL

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