Histone methyltransferase H3K79 Dot1l deletion effect on MLL-AF9 leukemia cells: time course - - GEO DataSets

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Histone methyltransferase H3K79 Dot1l deletion effect on MLL-AF9 leukemia cells: time course

Analysis of Mixed Lineage Leukemia (MLL)-AF9 leukemia cells after loss of Dot1l for up to 7 days. Loss of Dot1l leads to decreased growth, differentiation, and apoptosis of MLL-AF9 cells. Results provide insight into role of Dot1l in MLL-rearranged leukemia.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation, 3 time sets

Platform:: GPL1261
Series:: GSE25911
26 Samples

Download data: CEL

DataSet

Accession:: GDS4295

ID:: 4295

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