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Full record GDS4295

Histone methyltransferase H3K79 Dot1l deletion effect on MLL-AF9 leukemia cells: time course

Analysis of Mixed Lineage Leukemia (MLL)-AF9 leukemia cells after loss of Dot1l for up to 7 days. Loss of Dot1l leads to decreased growth, differentiation, and apoptosis of MLL-AF9 cells. Results provide insight into role of Dot1l in MLL-rearranged leukemia.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 3 time sets
Platform:
GPL1261
Series:
GSE25911
26 Samples
Download data: CEL

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