GEO DataSets

Analysis of U937 cells transfected with GFP-(PML-RAR)α (PR) or GFP-PR2VR (cleavage-resistant mutant) and GFP-sorted at 6 and 9 hrs. Neutrophil elastase (NE) cleaves PR, the fusion protein that initiates acute promyelocytic leukemia. Results provide insight into leukemogenicity of NE-resistant PR.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 genotype/variation, 2 time sets

Platform:

GPL570

Series:

GSE21550

12 Samples

Download data: CEL