U.S. flag

An official website of the United States government

Links from GEO Profiles

Full record GDS4172

Effect of protease-resistant (PML-RAR)α on U937 cell line

Analysis of U937 cells transfected with GFP-(PML-RAR)α (PR) or GFP-PR2VR (cleavage-resistant mutant) and GFP-sorted at 6 and 9 hrs. Neutrophil elastase (NE) cleaves PR, the fusion protein that initiates acute promyelocytic leukemia. Results provide insight into leukemogenicity of NE-resistant PR.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 genotype/variation, 2 time sets
Platform:
GPL570
Series:
GSE21550
12 Samples
Download data: CEL

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center
External link. Please review our privacy policy.