H3K79 histone methyl transferase DOT1L inhibitor Compound 55 effect on breast cancer cells: dose response - - GEO DataSets

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H3K79 histone methyl transferase DOT1L inhibitor Compound 55 effect on breast cancer cells: dose response

Analysis of MDA-MB-231 breast cancer cells treated with DOT1L (disruptor of telomeric silencing 1 like) inhibitor Compound 55 or DOT1L siRNA. DOT1L is a histone H3-lysine79 (H3K79) methyltransferase. Results provide insight into the role of DOT1L/H3K79 methylation in breast cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent, 4 dose sets

Platform:: GPL10558
Series:: GSE56630
8 Samples

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Accession:: GDS5620

ID:: 5620

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