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Full record GDS5332

Death receptor knockout effect on NEMO-deficient model of chronic liver disease

Analysis of livers from hepatocyte-specific NF-ĸB essential modulator (NEMO), NEMO-TRIAL, and NEMO-TNFR null males. NEMO deletion in hepatocytes causes spontaneous hepatocyte apoptosis. TNFR1 and TRAIL encode death receptors. Results provide insight into the role of death receptors in liver injury.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 genotype/variation sets
Platform:
GPL6246
Series:
GSE33161
11 Samples
Download data: CEL

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