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Full record GDS5271

Lipopolysaccharide effect on transmembrane protease, serine 6 deficient liver

Analysis of liver from Tmprss6 knockouts (KO) and iron-deficient WT littermates treated with LPS to induce acute inflammation. Tmprss6 KOs are iron-deficient with high levels of hepcidin, a key iron regulator. Results provide insight into molecular basis of the Tmprss6 KO inflammatory response.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 growth protocol, 2 stress sets
Platform:
GPL6887
Series:
GSE46287
12 Samples
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