SW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course - - GEO DataSets

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SW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course

Analysis of SW480 cancer cells treated with tankyrase inhibitor, MEK inhibitor, or both, for up to 16hrs. Dual inhibition of TNKS and MEK led to tumor regression. Results provide insight into molecular mechanisms underlying the synergistic effects of TNKS and MEK inhibitors in KRAS-mutant cancers.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 5 protocol, 3 time sets

Platform:: GPL570
Series:: GSE55624
18 Samples

Download data: CEL

DataSet

Accession:: GDS5029

ID:: 5029

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