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Full record GDS4771

High fat diet effect on liver depleted of promyelocytic leukemia gene

Analysis of livers from promyelocytic leukemia (Pml)-knockouts fed a high fat diet (HFD) for 20 wks. The increased predisposition of Pml-KOs to HFD-induced obesity is associated with aspects of metabolic syndrome. Results provide insight into molecular basis of a metabolic prosurvival role for PML.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
Platform:
GPL11180
Series:
GSE39220
12 Samples
Download data: CEL, CHP

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