GEO DataSets

Comparison of high endothelial venules endothelial cells (HEVEC) freshly isolated from tonsils with dedifferentiated HEVEC cultured ex vivo for 48 hours identifies gene expression controlled by tissue microenvironment.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 cell type, 2 growth protocol sets

Platform:

GPL127

Series:

GSE751

5 Samples

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(Submitter supplied) A double screen has been carried out by comparing freshly isolated HEVEC (D0-Hevec) from human tonsils to freshly purified HUVEC (D0-Huvec), and to dedifferentiated HEVEC (D2-Hevec) grown ex vivo for two days, using three Clontech commercial nucleotide arrays (Atlas Human Cardiovascular, 1.2 I and 1.2II Arrays) Keywords = freshly isolated HEVEC expression profile Keywords = HEVEC dedifferentiation ex vivo Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS622 GDS623 GDS624

Platforms:

GPL127 GPL128 GPL549

16 Samples

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Comparison of high endothelial venules endothelial cells (HEVEC) freshly isolated from tonsils with dedifferentiated HEVEC cultured ex vivo for 48 hours identifies gene expression controlled by tissue microenvironment.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 cell type, 2 growth protocol sets

Platform:

GPL549

Series:

GSE751

6 Samples

Download data

Comparison of high endothelial venules endothelial cells (HEVEC) freshly isolated from tonsils with dedifferentiated HEVEC cultured ex vivo for 48 hours identifies gene expression controlled by tissue microenvironment.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 cell type, 2 growth protocol sets

Platform:

GPL128

Series:

GSE751

5 Samples

Download data

(Submitter supplied) High endothelial venules (HEVs) are specialized blood vessels allowing recirculation of naïve lymphocytes through lymphoid organs. Here, using full length single-cell RNA sequencing, RNA-FISH, flow cytometry and immunohistofluorescence, we reveal the heterogeneity of HEVs in adult mouse peripheral lymph nodes (PLNs) under conditions of homeostasis, antigenic stimulation and after inhibition of lymphotoxin-b receptor (LTbR) signaling. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL21493

220 Samples

Download data: TXT

(Submitter supplied) Liver sinusoidal endothelium (LSEC) is a prime example for organ-specific microvascular differentiation and functions. Disease-associated capillarization of LSEC in vivo and dedifferentiation of LSEC in vitro indicate the importance of the hepatic microenvironment. To identify the LSEC-specific molecular differentiation program in the rat, we used a two-sided gene expression profiling approach comparing LSEC freshly isolated ex vivo with both lung microvascular endothelial cells (LMEC) and with LSEC cultured for 42h. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL8597

18 Samples

Download data: CEL