GEO DataSets

Analysis of ectopic endometria and eutopic endometria from endometriosis patients. Endometriosis is characterized by the presence of endometrial tissue at extra-uterine sites. Results provide insight into the molecular mechanisms underlying endometriosis pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 3 tissue sets

Platform:

GPL571

Series:

GSE25628

22 Samples

Download data: CEL

(Submitter supplied) Endometriosis is a complex pathological condition in which multiple components are involved in the disease development and clinical outcome. Endometriosis is mainly an inflammatory codition estrogen-dependent, with unknown pathogenesis, that is characterized by dissemination of edometrium tissue in ectopic position (ovary or pelvic peritoneum). Two main theories rise the pathologic onset: the presence of retrograde menstruation and celomic metaplasia in the pelvic peritoneum, that can occur for development defects. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS5339

Platform:

GPL571

22 Samples

Download data: CEL

(Submitter supplied) Brief description of the experiment: The objective of this experiment was to use DNA microarrays to identify differentially expressed genes in eutopic uterine endometrium compared to ectopic endometrium. 174 of the 53,000 genes on the whole human DNA microarrays were changed by 5-fold or greater in ectopic vs. eutopic endometrium. Families of genes that were differentially expressed include immune system and inflammatory pathway genes, genes whose cognate proteins code for cell adhesion, junctional proteins, the extracellular matrix and its remodeling, and cytoskeletal proteins, and ligands, receptors, and components of specific signal transduction pathways. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3092

Platform:

GPL2895

22 Samples

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Analysis of ectopic endometrial tissues implanted in the peritoneal cavity of 11 subjects. The growth of endometrial tissue outside of the uterus is called endometriosis. Results provide insight into the molecular pathology of endometriosis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 11 individual sets

Platform:

GPL2895

Series:

GSE5108

22 Samples

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