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Links from GEO DataSets

Items: 5

1.
Full record GDS4521

Ischemic stroke: peripheral blood mononuclear cells

Analysis of PBMCs collected from ischemic stroke (IS) patients at least 6 months after the first and only stroke event. Stroke is a complex disease resulting from the interplay of environmental and genetic factors. Results provide insight into the molecular mechanisms underlying IS etiology.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL570
Series:
GSE22255
40 Samples
Download data: CEL
2.

Blood genomic expression profile for ischemic stroke (IS)

(Submitter supplied) Stroke is a “brain attack” cutting off vital blood, and consequently the nutrients and oxygen vital to the brain cells that control everything we do. Stroke is a complex disease with unclear pathogenesis resulting from environmental and genetic factors. To better understand IS´s etiology, we performed genomic expression profiling of patients and controls.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4521
Platform:
GPL570
40 Samples
Download data: CEL
Series
Accession:
GSE22255
ID:
200022255
3.

Differential epigenetic profiling of human aortic endothelial cells (HAEC) in response to shear stress forces

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
32 Samples
Download data: BED
Series
Accession:
GSE112340
ID:
200112340
4.

Differential epigenetic profiling of human aortic endothelial cells (HAEC) in response to shear stress forces using ChIP-Seq of H3K27ac

(Submitter supplied) Biomechanical cues dynamically control major cellular processes but whether genetic variants actively participate in the mechano-sensing mechanisms remain unexplored. Vascular homeostasis is tightly regulated by hemodynamic forces. Exposure to disturbed blood flow at arterial sites of branching and bifurcation causes constant activation of vascular endothelium contributing to the development of atherosclerosis, the major cause of coronary artery disease (CAD). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
20 Samples
Download data: BED
Series
Accession:
GSE112336
ID:
200112336
5.

Differential epigenetic profiling of human aortic endothelial cells (HAEC) in response to shear stress forces using ATAC-Seq

(Submitter supplied) Biomechanical cues dynamically control major cellular processes but whether genetic variants actively participate in the mechano-sensing mechanisms remain unexplored. Vascular homeostasis is tightly regulated by hemodynamic forces. Exposure to disturbed blood flow at arterial sites of branching and bifurcation causes constant activation of vascular endothelium contributing to the development of atherosclerosis, the major cause of coronary artery disease (CAD). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
12 Samples
Download data: BED
Series
Accession:
GSE112328
ID:
200112328
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