GEO DataSets

Analysis of blood plasma from patients with colorectal cancer. Results used to identify gene markers for colorectal cancer.

Organism:

Homo sapiens

Type:

Expression profiling by array, log ratio, 2 disease state sets

Platform:

GPL3014

Series:

GSE4988

20 Samples

Download data: GPR

(Submitter supplied) Gene expression profiling of circulating plasma RNA is a valuable tool to detect cancer and a potential clinical instrument to study tumor progression and therapy responsiveness. In this study, differential gene expression analysis was used to identify genes specifically increased in cancer patients. Keywords: Disease state analysis

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2918

Platform:

GPL3014

20 Samples

Download data: GPR

(Submitter supplied) Liquid biopsy profile which can screen for early CRC. We aimed to depict the profile of early stage CRC as well as for advanced adenomas by combination of current molecular knowledge with microarray technology, using efficient circulating free RNA purification from blood and RNA amplification technologies. Circulating free RNA profile of plasma from colorectal cancer patients, advanced adenomas and healthy colonoscopia subjects.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10739

10 Samples

Download data: CEL, TXT, XLSX

(Submitter supplied) Colorectal cancer (CRC) is a genetically heterogeneous disease with several distinct morphological growth patterns. This study was aimed to investigate genes differentially expressed between ulcerative and polypoid colorectal CRC. cDNA microarray was first employed to compare the gene expression profiling of ulcerative and polypoid CRC with paired normal mucosa. Potential candidates identified by data filtering were further validated using quantitative real-time polymerase chain reaction, western blot and immunohistochemistry. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL17157

16 Samples

Download data: GPR

(Submitter supplied) MicroRNAs (miRNAs) are small non-coding RNA molecules which function as negative gene regulators. The tissue expression profile of miRNAs shows great promise as a novel biomarker for diagnosis of cancer and other diseases. In addition, some recent reports have demonstrated that are present in human serum and plasma which could make them an ideal non-invasive biomarker for diagnosis of cancer. The aim of this study is to analyze the value/efficacy of the expression profile of plasma miRNAs in differentiating between patients with advanced adenomas and CRC and healthy individuals.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL8179

77 Samples

Download data: TXT

(Submitter supplied) Detection, treatment, and prediction of outcome for lung cancer patients increasingly depend on a molecular understanding of tumor development and sensitivity of lung cancer to therapeutic drugs. The application of genomic technologies, such as microarray, is widely used to monitor global gene expression and has built up invaluable information and knowledge, which is essential to the discovery of new insights into the mechanisms common to cancer cells, resulting in the identification of unique, identifiable signatures and specific characteristics. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

66 Samples

Download data: CEL, EXP

(Submitter supplied) Global microRNA expression profiling of serum were collected using Agilent miRNA microarrays (G4471A Human, Amadid 29297, Sanger 14) carrying 887 individual human miRNA probes. Two different sources of RNA were analyzed: serum from NMRI-nu/nu mice carrying a xenograft tumor derived from human primary pancreatic ductal adenocarcinomas (CA, n=6) and serum from tumor free control NMRI-nu/nu mice (N, n=6)

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL14943

12 Samples

Download data: TXT

(Submitter supplied) Comparative expression analysis of RNA isolated from microvesicles from serum from glioblastoma multiforme (GBM) patients and normal healthy individuals.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL8755

16 Samples

Download data: TXT