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Links from GEO DataSets

Items: 3

1.
Full record GDS2858

Myeloid-related protein 8 and 14 effect on microvascular endothelial cells

Analysis of microvascular endothelial cells (ECs) treated with the myeloid-related protein 8 (MRP8) and 14 (MRP14), proteins that form heterodimers secreted by phagocytes at inflammatory sites. Results provide insight into the role of MRP8 and MRP14 in EC cell death during inflammation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL8300
Series:
GSE5474
8 Samples
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DataSet
Accession:
GDS2858
ID:
2858
2.

HMEC gene profile after stimulation with MRP8/MRP14

(Submitter supplied) Generating the gene expression profile of MRP8/MRP14-stimulated HMEC monolayer. Keywords: stress response
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2858
Platform:
GPL8300
8 Samples
Download data
Series
Accession:
GSE5474
ID:
200005474
3.

Genome-wide expression analysis demonstrates a dominant role of TLR4 for activation of human phagocytes by the alarmin MRP8

(Submitter supplied) The alarmins myeloid-related protein (MRP) 8 and MRP14 are the dominant cytoplasmic proteins in phagocytes. After release by activated phagocytes extracellular MRP8/MRP14 complexes promote inflammation in many diseases, including infections, allergies, autoimmune diseases, rheumatoid arthritis or inflammatory bowel disease. As receptors for the pro-inflammatory effects of human MRP8, the active component of the MRP8/MRP14-complex, Toll-like receptor (TLR) 4 and the multi-ligand receptor of advanced glycation end products (RAGE) are controversial discussed. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL96 GPL570
19 Samples
Download data: CEL
Series
Accession:
GSE56681
ID:
200056681
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Supplemental Content

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