U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 4

1.

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol

(Submitter supplied) Background: Alcohol misuse, binge drinking pattern, and gender-specific effects in the middle-aged population has been clearly underestimated. In the present study, we focused on understanding gender-specific effects of alcohol exposure on the gut-liver axis and the role of gut microbiota in modulating gender-specific responses to alcohol consumption. Methods: Fifty-two-week-old female and male C57BL/6 mice were fasted for 12 h, and then administered a single oral dose of ethanol (EtOH) (6 g/kg). more...
Organism:
mouse gut metagenome
Type:
Other
Platform:
GPL34367
11 Samples
Download data: CSV
Series
Accession:
GSE263477
ID:
200263477
2.

Chronic alcohol-induced dysbiosis of the gut microbiota and gut metabolites impairs sperm quality

(Submitter supplied) Purpose: To explore whether chronic alcohol consumption affects sperm quality by inducing changes in the gut microbiota.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
6 Samples
Download data: TXT
Series
Accession:
GSE192522
ID:
200192522
3.

Prominent role of gut dysbiosis in the pathogenesis of cystic fibrosis-related liver disease in mice

(Submitter supplied) Cystic fibrosis-related liver disease (CFLD) is a chronic cholangiopathy that increases morbidity and mortality in patients with CF. Current treatments are unsatisfactory, and incomplete understanding of CFLD pathogenesis hampers therapeutic development. We have previously shown that mouse CF cholangiocytes respond with excessive inflammation to LPS. Thus, we investigated the role of the gut-liver axis in the pathogenesis of CFLD.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
9 Samples
Download data: MTX, TSV
Series
Accession:
GSE238000
ID:
200238000
4.

RNA-seq of three groups mice in livers.

(Submitter supplied) We sought to examine whether urolithin A could alleviate the alcohol-related liver disease. RNA-sequencing (RNA-seq) on mice livers were performed in order to identify the key biological processes and pathways regulated by urolithin A.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30215
15 Samples
Download data: TXT
Series
Accession:
GSE253307
ID:
200253307
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=3|blobid=MCID_6782d8350bdf8a6e7300ad86|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center