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Links from GEO DataSets

Items: 3

1.

Neural control of fluid homeostasis is engaged below 10°C in hibernation

(Submitter supplied) Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) hibernate for several months each winter without access to water, but the mechanisms that maintain fluid homeostasis during hibernation are poorly understood. In torpor, when body temperature (TB) reaches 4°C, squirrels decrease metabolism, slow heart rate, and reduce plasma levels of the antidiuretic hormones arginine vasopressin (AVP) and oxytocin (OXT). more...
Organism:
Ictidomys tridecemlineatus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30340
15 Samples
Download data: XLSX
Series
Accession:
GSE231418
ID:
200231418
2.

Hypothalamic thyroid hormone deficiency underlies reversible anorexia in a mammalian hibernator

(Submitter supplied) Mammalian hibernators survive prolonged periods of cold and resource scarcity by temporarily modulating normal physiological functions, but the mechanisms underlying these adaptations are poorly understood. The hibernation cycle of thirteen-lined ground squirrels lasts for 5–7 months and comprises weeks of hypometabolic, hypothermic torpor interspersed with 24–48-hour periods of an active-like interbout arousal (IBA) state. more...
Organism:
Ictidomys tridecemlineatus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30340
6 Samples
Download data: TAR
Series
Accession:
GSE242381
ID:
200242381
3.

Activation of immediate early response genes initiates a restorative gene expression program during each arousal from torpor in hibernating 13-lined ground squirrels

(Submitter supplied) RNA-seq libraries were prepared from replicate samples (n=5-6) from six physiolocial groups to capture key changes in circannual hibernation.
Organism:
Ictidomys tridecemlineatus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24271 GPL30340
31 Samples
Download data: TSV
Series
Accession:
GSE207211
ID:
200207211
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