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Links from GEO DataSets

Items: 20

1.

CD95/Fas ligand mRNA is toxic to cells through more than one mechanism [DISE-46]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in a HCT116 wild-type, Drosha k.o., and Dicer k.o. cells expressing pLenti-CD95L NP or pLenti empty vector.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
6 Samples
Download data: TXT
Series
Accession:
GSE219222
ID:
200219222
2.

CD95/Fas ligand mRNA is toxic to cells through more than one mechanism

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
36 Samples
Download data
Series
Accession:
GSE219226
ID:
200219226
3.

CD95/Fas ligand mRNA is toxic to cells through more than one mechanism [DISE-64]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in a HCT116 Drosha CD95 d.k.o. cell line expressing pLenti-CD95L and various CD95L mutant constructs.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
8 Samples
Download data: TXT
Series
Accession:
GSE219225
ID:
200219225
4.

CD95/Fas ligand mRNA is toxic to cells through more than one mechanism [DISE-63]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in a HCT116 wild-type, Drosha k.o., and Ago 1/2/3 k.o. cells expressing pLenti-CD95L NP or pLenti empty vector.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
12 Samples
Download data: TXT
Series
Accession:
GSE219224
ID:
200219224
5.

CD95/Fas ligand mRNA is toxic to cells through more than one mechanism [DISE-47]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in a HCT116 Drosha CD95 d.k.o. cell line expressing pLenti-CD95L and various CD95L mutant constructs.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
10 Samples
Download data: TXT
Series
Accession:
GSE219223
ID:
200219223
6.

CD95L mRNA is toxic to cells

(Submitter supplied) >80% of a large number of tested siRNAs and shRNAs targeting CD95 or CD95 ligand (CD95L) induce a form of cell death that is characterized by the simultaneous activation of multiple death pathways and preferentially affects transformed and cancer stem cells. We now show that these si/shRNAs kill cancer cells through canonical RNAi by targeting the 3’UTR of critical survival genes in a unique form of off-target effect. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL21290
12 Samples
Download data: XLSX
7.

CD95/Fas ligand mRNA is toxic to cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL20301
12 Samples
Download data
Series
Accession:
GSE103631
ID:
200103631
8.

CD95L mRNA is toxic to cells [SmallRNA.CD95L.50hrs.HeyA8]

(Submitter supplied) >80% of a large number of tested siRNAs and shRNAs targeting CD95 or CD95 ligand (CD95L) induce a form of cell death that is characterized by the simultaneous activation of multiple death pathways and preferentially affects transformed and cancer stem cells. We now show that these si/shRNAs kill cancer cells through canonical RNAi by targeting the 3’UTR of critical survival genes in a unique form of off-target effect. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
4 Samples
Download data: XLSX
Series
Accession:
GSE102780
ID:
200102780
9.

CD95L mRNA is toxic to cells [SmallRNA_CD95L.50hrs.Drosha_ko]

(Submitter supplied) >80% of a large number of tested siRNAs and shRNAs targeting CD95 or CD95 ligand (CD95L) induce a form of cell death that is characterized by the simultaneous activation of multiple death pathways and preferentially affects transformed and cancer stem cells. We now show that these si/shRNAs kill cancer cells through canonical RNAi by targeting the 3’UTR of critical survival genes in a unique form of off-target effect. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
4 Samples
Download data: XLSX
Series
Accession:
GSE102779
ID:
200102779
10.

CD95L mRNA is toxic to cells [SmallRNA_AGOpulldownCD95L_50hrs_HeyA8_CD95KO]

(Submitter supplied) >80% of a large number of tested siRNAs and shRNAs targeting CD95 or CD95 ligand (CD95L) induce a form of cell death that is characterized by the simultaneous activation of multiple death pathways and preferentially affects transformed and cancer stem cells. We now show that these si/shRNAs kill cancer cells through canonical RNAi by targeting the 3’UTR of critical survival genes in a unique form of off-target effect. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL20301
4 Samples
Download data: XLS
11.

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL20301
68 Samples
Download data
Series
Accession:
GSE218195
ID:
200218195
12.

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity (DISE-69)

(Submitter supplied) Analysis of total RNA by RNA seq
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
4 Samples
Download data: XLSX
Series
Accession:
GSE218194
ID:
200218194
13.

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-56]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in cells infected with HIV-1 reveals a contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing; Other
Platform:
GPL20301
18 Samples
Download data: TXT
Series
Accession:
GSE218193
ID:
200218193
14.

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity (DISE-45)

(Submitter supplied) Analysis of RISC bound short (s)RNAs in cells infected with HIV-1 reveals a contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing; Other
Platform:
GPL20301
12 Samples
Download data: TXT
Series
Accession:
GSE218192
ID:
200218192
15.

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-42]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in cells infected with HIV-1 reveals a contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing; Other
Platform:
GPL20301
18 Samples
Download data: TXT
Series
Accession:
GSE218191
ID:
200218191
16.

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-36]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in cells infected with HIV-1 reveals a contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing; Other
Platform:
GPL20301
8 Samples
Download data: TXT
Series
Accession:
GSE218189
ID:
200218189
17.

Contribution of 6mer seed toxicity to HIV-1 induced cytotoxicity [DISE-19]

(Submitter supplied) Analysis of RISC bound short (s)RNAs in cells infected with HIV-1 reveals a contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing; Other
Platform:
GPL20301
8 Samples
Download data: TXT
Series
Accession:
GSE218187
ID:
200218187
18.

Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer's disease and aging

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL21103 GPL20301
60 Samples
Download data
Series
Accession:
GSE213138
ID:
200213138
19.

Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer's disease and aging

(Submitter supplied) Analysis of RISC bound short (s)RNAs in various cell lines and mouse models of Alzheimer's disease and in human AD patients reveals a contribution of 6mer seed toxicity to the neurotoxicity associated with AD
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL20301
9 Samples
Download data: TXT
Series
Accession:
GSE213137
ID:
200213137
20.

Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer's disease and aging

(Submitter supplied) Analysis of RISC bound short (s)RNAs in various cell lines and mouse models of Alzheimer's disease and in human AD patients reveals a contribution of 6mer seed toxicity to the neurotoxicity associated with AD
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL20301
12 Samples
Download data: TXT
Series
Accession:
GSE213136
ID:
200213136
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