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Links from GEO DataSets

Items: 3

1.

Dysbacteriosis-induced LPS elevation disturbs the development of muscle progenitor cells by interfering with retinoic acid signaling [16S rRNA sequencing]

(Submitter supplied) Whether myogenesis is affected by the maternal gut dysbacteriosis still remains ambiguous. In this study, firstly we show elevated level of lipopolysaccharides (LPS) in a gut microbiota dysbiosis mouse model. Secondly, we demonstrate that the diameter of muscle fibres, limb development and somitogenesis were inhibited in both gut microbiota dysbiosis and LPS exposed mice and chicken embryos. These might be due to LPS disturbed the cell survival and the key genes which regulating the somitogenesis and myogenesis. more...
Organism:
mouse gut metagenome
Type:
Other
Platform:
GPL27659
7 Samples
Download data: FNA, TXT
Series
Accession:
GSE139422
ID:
200139422
2.

Dysbacteriosis-induced LPS elevation disturbs the development of muscle progenitor cells by interfering with retinoic acid signaling

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
mouse gut metagenome; Gallus gallus
Type:
Other; Expression profiling by high throughput sequencing
Platforms:
GPL27659 GPL23499
13 Samples
Download data: FNA
Series
Accession:
GSE139526
ID:
200139526
3.

Dysbacteriosis-induced LPS elevation disturbs the development of muscle progenitor cells by interfering with retinoic acid signaling [RNA-seq]

(Submitter supplied) Whether myogenesis is affected by the maternal gut dysbacteriosis still remains ambiguous. In this study, firstly we show elevated level of lipopolysaccharides (LPS) in a gut microbiota dysbiosis mouse model. Secondly, we demonstrate that the diameter of muscle fibres, limb development and somitogenesis were inhibited in both gut microbiota dysbiosis and LPS exposed mice and chicken embryos. These might be due to LPS disturbed the cell survival and the key genes which regulating the somitogenesis and myogenesis. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23499
6 Samples
Download data: TXT
Series
Accession:
GSE139525
ID:
200139525
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