Similar studies for GEO DataSets (Select 200133837) - GEO DataSets

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Items: 2

Select item 2001338371.

Complete LKB1 loss results in lethal metastatic prostate cancer

(Submitter supplied) In order to identify the contribution of Lkb1 loss to Pten driven prostate cancer progression, we engineered a prostate conditional mutant mice in which was induced the loss of Lkb1 in combination with heterozygous loss of the prostate tumor suppressor Pten (Ptenpc+/- Lkb1pc-/-). This mouse model developed metastatic prostate squamous cell carcinoma. We compared this tumor type with the adenocarcinomas developed in Ptenpc-/- Lkb1pc+/+ mice. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL20258
13 Samples

Download data: CEL

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Accession:: GSE133837

ID:: 200133837

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000725492.

Gene expression profiling of prostate tissues and seminal vesicles from PB-Pten-NICD mice

(Submitter supplied) To investigate the identity of the tissue origin for metastases, we compared gene expression profiles of the prostate tissues and seminal vesicles from PB-Pten-NICD mice and those of 7 lung metastases from different mice. Three respective cell lines established from primary seminal vesicle tumors, primary prostate tumors, and lung metastases in PB-Pten-NICD mice were also included in the microarray analysis. more...